Evaluation of laboratory profiles of hemodialysis patients in Zawia Kidney Center

Abstract

BackgroundChronickidneydisease (CKD) defined as sustained damage of renalparenchymaleading to a chronicdeterioration of renalfunctionthatmaygraduallyprogress to end-stage renaldisease (ESRD). Kidneydiseaseisnowconsidered as a global public healthepidemicthat leads to increase incidences of morbidity and mortality. Aim: This studyaimed to evaluate the kidneyfunctionparameters of CKD patients includinguricacid, creatinine, urea, protein, and Glomerular filtration. Materials and Methods:Data frommedical records of the 54 patients’ follow-up attending the dialysis department, Zawia Kidney Centreduring the period of the studyincludedbothdemographic data &laboratory test. Demographic data includingage, gender, blood group, and comorbiditydisorderwereobtainedfrom the patients.Biochemicalparametersincludinghemoglobin, creatinine, uricacid, serum total protein and potassium werealsoinvestigated. Results:The majority of patients with CKD (35.5 %) werewithin the (36-46) age group. (53.7%) of them have blood group O+ followed by 18.5% of the A+ blood group. The prevalence of CKD in females (70%) more than males (30%) in thisstudy. The resultalsofoundthat32.7 % of patients have diabetes and 17.2% have hypertension whereas%20.6suffersfromboth. Hemoglobinlevelwassignificantlylower (8.318 g/dL) (p<0.05) whereas, creatinine, uricacid and serum total proteinlevelswerehigher (6.407mg/dL, 6.106mmol/L,5.759 g/dL) respectively). Conclusions: Patients on maintenance dialysis have a high incidence and prevalence of diabetes, hypertension and anemia. A Large proportion of the patients have O+. These patients also have abnormallaboratory tests. Therefore, special care needs to betaken to improve the health of dialysis patients.